Process Chemistry

Alphora operates well equipped, state of the art synthetic laboratories, that allow our chemists to develop and scale-up the most complex syntheses. Access to key analytical instrumentation and preparative chromatography systems for isolating materials is imperative to understanding and solving key fundamental chemical challenges.

 

Alphora's R&D team has considerable experience developing highly complex syntheses as well as providing process optimization expertise for challenging API development programs.

 

Process Hazards Laboratory Prior to introducing a process into a scale-up facility Alphora's scientists assesses safety considerations that may be harmful and potentially explosive. This approach prevents personal injury, as well ensures there are no unexpected delays to our Client's programs

 

Equipment


  • 24 Fume Hoods and Walk-in Hoods
  • 300 MHZ Bruker NMR (H,C,F,P)
  • SD-2 Varian Prep HPLC, 200ml/min
  • 75M Flash Biotage LC
  • Isolera-1 Biotage LC
  • 6"x 4ft Static Chromatography Columns
  • 0.5 to 4L Parr Hydrogenators
  • HEL Thermal Screening Unit
  • MultiMax™ - Automated Process Development and Calorimetry Tool
  • LC/MS: Agilent 1200 HPLC Interfaced with Agilent XCT Ultra Ion Trap (High Sensitivity Trap Capable of Performing Multiple MS/MS Stages)
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